Systemic scleroderma
SCLERODERMA THAT IS CHARACTERIZED BY FIBROSIS (OR HARDENING) OF THE SKIN AND MAJOR ORGANS, AS WELL AS VASCULAR ALTERATIONS, AND AUTOANTIBODIES
Systemic sclerosis; Systemic Sclerosis in Greece; SSc; Progressive systemic sclerosis; Systemic sclerosis (scleroderma); Diffuse cutaneous type systemic sclerosis; Diffuse cutaneous systemic sclerosis
Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse.